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A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel

The swelling-activated anion channel VRAC has fascinated and frustrated physiologists since it was first described in 1988. Multiple laboratories have defined VRAC’s biophysical properties and have shown that it plays a central role in cell volume regulation and possibly other fundamental physiologi...

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Detalles Bibliográficos
Autores principales:	Strange, Kevin, Yamada, Toshiki, Denton, Jerod S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363415/ https://www.ncbi.nlm.nih.gov/pubmed/30651298 http://dx.doi.org/10.1085/jgp.201812138

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