Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels

Batrachotoxin (BTX), an alkaloid from skin secretions of dendrobatid frogs, causes paralysis and death by facilitating activation and inhibiting deactivation of eukaryotic voltage-gated sodium (Nav) channels, which underlie action potentials in nerve, muscle, and heart. A full understanding of the m...

Descripción completa

Detalles Bibliográficos
Autores principales: Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Goldschen-Ohm, Marcel P., Gaudet, Rachelle, Tikhonov, Denis B., Zhorov, Boris S., French, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363421/
https://www.ncbi.nlm.nih.gov/pubmed/30587506
http://dx.doi.org/10.1085/jgp.201812278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363421/
https://www.ncbi.nlm.nih.gov/pubmed/30587506
http://dx.doi.org/10.1085/jgp.201812278

Ejemplares similares