Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer

PIK3CA is the most commonly altered oncogene in head and neck squamous cell carcinoma (HNSCC). We evaluated the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on survival in a PIK3CA-characterized cohort of 266 HNSCC patients and explored the mechanism in relevant preclinical models includi...

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Detalles Bibliográficos
Autores principales: Hedberg, Matthew L., Peyser, Noah D., Bauman, Julie E., Gooding, William E., Li, Hua, Bhola, Neil E., Zhu, Tian Ran, Zeng, Yan, Brand, Toni M., Kim, Mi-Ok, Jordan, Richard C.K., VandenBerg, Scott, Olivas, Victor, Bivona, Trever G., Chiosea, Simion I., Wang, Lin, Mills, Gordon B., Johnson, Jonas T., Duvvuri, Umamaheswar, Ferris, Robert L., Ha, Patrick, Johnson, Daniel E., Grandis, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363423/
https://www.ncbi.nlm.nih.gov/pubmed/30683736
http://dx.doi.org/10.1084/jem.20181936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363423/
https://www.ncbi.nlm.nih.gov/pubmed/30683736
http://dx.doi.org/10.1084/jem.20181936

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