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Self-reactive CD4(+) IL-3(+) T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis

Acquisition of self-reactive effector CD4(+) T cells is a major component of the autoimmune response that can occur during myocarditis, an inflammatory form of cardiomyopathy. Although the processes by which self-reactive T cells gain effector function have received considerable attention, how these...

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Detalles Bibliográficos
Autores principales: Anzai, Atsushi, Mindur, John E., Halle, Lennard, Sano, Soichi, Choi, Jennifer L., He, Shun, McAlpine, Cameron S., Chan, Christopher T., Kahles, Florian, Valet, Colin, Fenn, Ashley M., Nairz, Manfred, Rattik, Sara, Iwamoto, Yoshiko, Fairweather, DeLisa, Walsh, Kenneth, Libby, Peter, Nahrendorf, Matthias, Swirski, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363430/
https://www.ncbi.nlm.nih.gov/pubmed/30670465
http://dx.doi.org/10.1084/jem.20180722