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Immune regulation by glucocorticoids can be linked to cell type–dependent transcriptional responses

Glucocorticoids remain the most widely used immunosuppressive and anti-inflammatory drugs, yet substantial gaps exist in our understanding of glucocorticoid-mediated immunoregulation. To address this, we generated a pathway-level map of the transcriptional effects of glucocorticoids on nine primary...

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Detalles Bibliográficos
Autores principales: Franco, Luis M., Gadkari, Manasi, Howe, Katherine N., Sun, Jing, Kardava, Lela, Kumar, Parag, Kumari, Sangeeta, Hu, Zonghui, Fraser, Iain D.C., Moir, Susan, Tsang, John S., Germain, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363437/
https://www.ncbi.nlm.nih.gov/pubmed/30674564
http://dx.doi.org/10.1084/jem.20180595