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Retromer has a selective function in cargo sorting via endosome transport carriers

Retromer is a peripheral membrane protein complex that coordinates multiple vesicular trafficking events within the endolysosomal system. Here, we demonstrate that retromer is required for the maintenance of normal lysosomal morphology and function. The knockout of retromer subunit Vps35 causes an u...

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Detalles Bibliográficos
Autores principales: Cui, Yi, Carosi, Julian M., Yang, Zhe, Ariotti, Nicholas, Kerr, Markus C., Parton, Robert G., Sargeant, Timothy J., Teasdale, Rohan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363445/
https://www.ncbi.nlm.nih.gov/pubmed/30559172
http://dx.doi.org/10.1083/jcb.201806153