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TPX2 joins 53BP1 to maintain DNA repair and fork stability

In this issue, Byrum et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201803003) surprisingly identify an interaction between 53BP1 and the mitotic regulators TPX2 and Aurora A that lead them to novel mechanistic insights about DNA double-stranded break repair regulation and a new fork protec...

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Detalles Bibliográficos
Autor principal: Cantor, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363450/
https://www.ncbi.nlm.nih.gov/pubmed/30635354
http://dx.doi.org/10.1083/jcb.201812142