Single event visualization of unconventional secretion of FGF2

FGF2 is exported from cells by an unconventional secretory mechanism. Here, we directly visualized individual FGF2 membrane translocation events at the plasma membrane using live cell TIRF microscopy. This process was dependent on both PI(4,5)P(2)–mediated recruitment of FGF2 at the inner leaflet an...

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Detalles Bibliográficos
Autores principales: Dimou, Eleni, Cosentino, Katia, Platonova, Evgenia, Ros, Uris, Sadeghi, Mohsen, Kashyap, Purba, Katsinelos, Taxiarchis, Wegehingel, Sabine, Noé, Frank, García-Sáez, Ana J., Ewers, Helge, Nickel, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363455/
https://www.ncbi.nlm.nih.gov/pubmed/30470711
http://dx.doi.org/10.1083/jcb.201802008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363455/
https://www.ncbi.nlm.nih.gov/pubmed/30470711
http://dx.doi.org/10.1083/jcb.201802008

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