Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells

Many adult tissues contain postmitotic cells as old as the host organism. The only organelle that does not turn over in these cells is the nucleus, and its maintenance represents a formidable challenge, as it harbors regulatory proteins that persist throughout adulthood. Here we developed strategies...

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Detalles Bibliográficos
Autores principales: Toyama, Brandon H., Arrojo e Drigo, Rafael, Lev-Ram, Varda, Ramachandra, Ranjan, Deerinck, Thomas J., Lechene, Claude, Ellisman, Mark H., Hetzer, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363465/
https://www.ncbi.nlm.nih.gov/pubmed/30552100
http://dx.doi.org/10.1083/jcb.201809123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363465/
https://www.ncbi.nlm.nih.gov/pubmed/30552100
http://dx.doi.org/10.1083/jcb.201809123

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