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Current strategies for targeting the activity of androgen receptor variants

Current therapies for advanced prostate cancer, such as enzalutamide and abiraterone, focus on inhibiting androgen receptor (AR) activity and reducing downstream signaling pathways to inhibit tumor growth. Unfortunately, cancer cells are very adaptable and, over time, these cells develop mechanisms...

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Detalles Bibliográficos
Autores principales: Armstrong, Cameron M., Gao, Allen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363599/
https://www.ncbi.nlm.nih.gov/pubmed/30775247
http://dx.doi.org/10.1016/j.ajur.2018.07.003