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Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) resident protein that can be secreted due to an imperfect KDEL motif. MANF plays a cytoprotective role in several soft tissues and is upregulated in conditions resulting from intracellular retention of mutant...

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Detalles Bibliográficos
Autores principales: Bell, P. A., Dennis, E. P., Hartley, C. L., Jackson, R. M., Porter, A., Boot-Handford, R. P., Pirog, K. A., Briggs, M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363614/
https://www.ncbi.nlm.nih.gov/pubmed/30543055
http://dx.doi.org/10.1007/s12192-018-0953-7