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Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) resident protein that can be secreted due to an imperfect KDEL motif. MANF plays a cytoprotective role in several soft tissues and is upregulated in conditions resulting from intracellular retention of mutant...
Autores principales: | Bell, P. A., Dennis, E. P., Hartley, C. L., Jackson, R. M., Porter, A., Boot-Handford, R. P., Pirog, K. A., Briggs, M. D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363614/ https://www.ncbi.nlm.nih.gov/pubmed/30543055 http://dx.doi.org/10.1007/s12192-018-0953-7 |
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