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A Comprehensive Analysis of Population Differences in LRRK2 Variant Distribution in Parkinson's Disease

Background: LRRK2 variants have been demonstrated to have distinct distributions in different populations. However, researchers have thus far chosen to focus on relatively few variants, such as R1628P, G2019S, and G2385R. We therefore investigated the relationship between common LRRK2 variants and P...

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Detalles Bibliográficos
Autores principales: Shu, Li, Zhang, Yuan, Sun, Qiying, Pan, Hongxu, Tang, Beisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363667/
https://www.ncbi.nlm.nih.gov/pubmed/30760999
http://dx.doi.org/10.3389/fnagi.2019.00013