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FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils

The function of the low-affinity IgG-receptor FcγRIIIb (CD16b), which is uniquely and abundantly expressed on human granulocytes, is not clear. Unlike the other Fcγ receptors (FcγR), it is a glycophosphatidyl inositol (GPI) -anchored molecule and does not have intracellular signaling motifs. Neverth...

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Detalles Bibliográficos
Autores principales: Treffers, Louise W., van Houdt, Michel, Bruggeman, Christine W., Heineke, Marieke H., Zhao, Xi Wen, van der Heijden, Joris, Nagelkerke, Sietse Q., Verkuijlen, Paul J. J. H., Geissler, Judy, Lissenberg-Thunnissen, Suzanne, Valerius, Thomas, Peipp, Matthias, Franke, Katka, van Bruggen, Robin, Kuijpers, Taco W., van Egmond, Marjolein, Vidarsson, Gestur, Matlung, Hanke L., van den Berg, Timo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363688/
https://www.ncbi.nlm.nih.gov/pubmed/30761158
http://dx.doi.org/10.3389/fimmu.2018.03124