CRP-Induced NLRP3 Inflammasome Activation Increases LDL Transcytosis Across Endothelial Cells

The NLRP3 inflammasome, a multiprotein cytosolic complex that activates the IL-1 family of cytokines, plays an important role in atherosclerosis (AS). High-sensitivity c-reactive protein (hs-CRP) is widely recognized as a major cardiovascular risk predictor and recent studies name NLRP3 as a predict...

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Detalles Bibliográficos
Autores principales: Bian, Fang, Yang, Xiao-Yan, Xu, Gao, Zheng, Tao, Jin, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363700/
https://www.ncbi.nlm.nih.gov/pubmed/30761006
http://dx.doi.org/10.3389/fphar.2019.00040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363700/
https://www.ncbi.nlm.nih.gov/pubmed/30761006
http://dx.doi.org/10.3389/fphar.2019.00040

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