Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

Sirtuins (SIRTs), class III histone deacetylases, are differentially expressed in several human cancers, where they display both oncogenic and tumor-suppressive properties depending on cellular context and experimental conditions. SIRTs are involved in many important biological processes and play a...

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Detalles Bibliográficos
Autores principales: Carafa, Vincenzo, Altucci, Lucia, Nebbioso, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363704/
https://www.ncbi.nlm.nih.gov/pubmed/30761005
http://dx.doi.org/10.3389/fphar.2019.00038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363704/
https://www.ncbi.nlm.nih.gov/pubmed/30761005
http://dx.doi.org/10.3389/fphar.2019.00038

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