Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity

Aging significantly increases the vulnerability to gastrointestinal (GI) disorders but there are few studies investigating the key factors in aging that affect the GI tract. To address this knowledge gap, we used 10-week- and 19-month-old litter-mate mice to investigate microbiota and host gene expr...

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Detalles Bibliográficos
Autores principales: Sovran, Bruno, Hugenholtz, Floor, Elderman, Marlies, Van Beek, Adriaan A., Graversen, Katrine, Huijskes, Myrte, Boekschoten, Mark V., Savelkoul, Huub F. J., De Vos, Paul, Dekker, Jan, Wells, Jerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363726/
https://www.ncbi.nlm.nih.gov/pubmed/30723224
http://dx.doi.org/10.1038/s41598-018-35228-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363726/
https://www.ncbi.nlm.nih.gov/pubmed/30723224
http://dx.doi.org/10.1038/s41598-018-35228-3

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