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Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity
Aging significantly increases the vulnerability to gastrointestinal (GI) disorders but there are few studies investigating the key factors in aging that affect the GI tract. To address this knowledge gap, we used 10-week- and 19-month-old litter-mate mice to investigate microbiota and host gene expr...
Autores principales: | Sovran, Bruno, Hugenholtz, Floor, Elderman, Marlies, Van Beek, Adriaan A., Graversen, Katrine, Huijskes, Myrte, Boekschoten, Mark V., Savelkoul, Huub F. J., De Vos, Paul, Dekker, Jan, Wells, Jerry M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363726/ https://www.ncbi.nlm.nih.gov/pubmed/30723224 http://dx.doi.org/10.1038/s41598-018-35228-3 |
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