Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression

Lung cancer remains the leading cause of cancer-related death, despite the advent of targeted therapies and immunotherapies. Therefore, it is crucial to identify novel molecular features unique to lung tumors. Here, we show that cyclopamine tartrate (CycT) strongly suppresses the growth of subcutane...

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Detalles Bibliográficos
Autores principales: Kalainayakan, Sarada Preeta, Ghosh, Poorva, Dey, Sanchareeka, Fitzgerald, Keely E., Sohoni, Sagar, Konduri, Purna Chaitanya, Garrossian, Massoud, Liu, Li, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363760/
https://www.ncbi.nlm.nih.gov/pubmed/30723259
http://dx.doi.org/10.1038/s41598-018-38345-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363760/
https://www.ncbi.nlm.nih.gov/pubmed/30723259
http://dx.doi.org/10.1038/s41598-018-38345-1

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