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Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron - specific molecular signatures

Midbrain dopaminergic (DA) neurons are involved in diverse neurological functions, including control of movements, emotions or reward. In turn, their dysfunctions cause severe clinical manifestations in humans, such as the appearance of motor and cognitive symptoms in Parkinson’s Disease. The physio...

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Detalles Bibliográficos
Autores principales: Gendron, J., Colace-Sauty, C., Beaume, N., Cartonnet, H., Guegan, J., Ulveling, D., Pardanaud-Glavieux, C., Moszer, I., Cheval, H., Ravassard, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363776/
https://www.ncbi.nlm.nih.gov/pubmed/30723217
http://dx.doi.org/10.1038/s41598-018-37872-1