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Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters

EPDR1, a member of the ependymin-related protein family, is a relatively uncharacterized protein found in the lysosomes and secretomes of most vertebrates. Despite having roles in human disease and health, the molecular functions of EPDR1 remain unknown. Here, we present crystal structures of human...

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Detalles Bibliográficos
Autores principales: Wei, Yong, Xiong, Zi Jian, Li, Jun, Zou, Chunxia, Cairo, Christopher W., Klassen, John S., Privé, Gilbert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363788/
https://www.ncbi.nlm.nih.gov/pubmed/30729188
http://dx.doi.org/10.1038/s42003-018-0262-9