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Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters
EPDR1, a member of the ependymin-related protein family, is a relatively uncharacterized protein found in the lysosomes and secretomes of most vertebrates. Despite having roles in human disease and health, the molecular functions of EPDR1 remain unknown. Here, we present crystal structures of human...
Autores principales: | Wei, Yong, Xiong, Zi Jian, Li, Jun, Zou, Chunxia, Cairo, Christopher W., Klassen, John S., Privé, Gilbert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363788/ https://www.ncbi.nlm.nih.gov/pubmed/30729188 http://dx.doi.org/10.1038/s42003-018-0262-9 |
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