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Targets of complement-fixing antibodies in protective immunity against malaria in children

Antibodies against P. falciparum merozoites fix complement to inhibit blood-stage replication in naturally-acquired and vaccine-induced immunity; however, specific targets of these functional antibodies and their importance in protective immunity are unknown. Among malaria-exposed individuals, we sh...

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Detalles Bibliográficos
Autores principales: Reiling, Linda, Boyle, Michelle J., White, Michael T., Wilson, Danny W., Feng, Gaoqian, Weaver, Rupert, Opi, D. Herbert, Persson, Kristina E. M., Richards, Jack S., Siba, Peter M., Fowkes, Freya J. I., Takashima, Eizo, Tsuboi, Takafumi, Mueller, Ivo, Beeson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363798/
https://www.ncbi.nlm.nih.gov/pubmed/30723225
http://dx.doi.org/10.1038/s41467-019-08528-z