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Targets of complement-fixing antibodies in protective immunity against malaria in children
Antibodies against P. falciparum merozoites fix complement to inhibit blood-stage replication in naturally-acquired and vaccine-induced immunity; however, specific targets of these functional antibodies and their importance in protective immunity are unknown. Among malaria-exposed individuals, we sh...
Autores principales: | Reiling, Linda, Boyle, Michelle J., White, Michael T., Wilson, Danny W., Feng, Gaoqian, Weaver, Rupert, Opi, D. Herbert, Persson, Kristina E. M., Richards, Jack S., Siba, Peter M., Fowkes, Freya J. I., Takashima, Eizo, Tsuboi, Takafumi, Mueller, Ivo, Beeson, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363798/ https://www.ncbi.nlm.nih.gov/pubmed/30723225 http://dx.doi.org/10.1038/s41467-019-08528-z |
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