Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

The ability of circulating tumor cells (CTCs) to form clusters has been linked to increased metastatic potential. Yet biological features and vulnerabilities of CTC clusters remain largely unknown. Here, we profile the DNA methylation landscape of single CTCs and CTC clusters from breast cancer pati...

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Detalles Bibliográficos
Autores principales: Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Aceto, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363966/
https://www.ncbi.nlm.nih.gov/pubmed/30633912
http://dx.doi.org/10.1016/j.cell.2018.11.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363966/
https://www.ncbi.nlm.nih.gov/pubmed/30633912
http://dx.doi.org/10.1016/j.cell.2018.11.046

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