HDAC6 Restricts Influenza A Virus by Deacetylation of the RNA Polymerase PA Subunit

The life cycle of influenza A virus (IAV) is modulated by various cellular host factors. Although previous studies indicated that IAV infection is controlled by HDAC6, the deacetylase involved in the regulation of PA remained unknown. Here, we demonstrate that HDAC6 acts as a negative regulator of I...

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Detalles Bibliográficos
Autores principales: Chen, Huan, Qian, Yingjuan, Chen, Xin, Ruan, Zhiyang, Ye, Yuetian, Chen, Hongjun, Babiuk, Lorne A., Jung, Yong-Sam, Dai, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364008/
https://www.ncbi.nlm.nih.gov/pubmed/30518648
http://dx.doi.org/10.1128/JVI.01896-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364008/
https://www.ncbi.nlm.nih.gov/pubmed/30518648
http://dx.doi.org/10.1128/JVI.01896-18

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