Cargando…

A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome

Defective interfering particles (DIPs) replicate at the expense of coinfecting, fully infectious homologous virus. Typically, they contain a highly deleted form of the viral genome. Utilizing single-cell analysis, here we report the discovery of a yet-unknown DIP type, derived from influenza A virus...

Descripción completa

Detalles Bibliográficos
Autores principales: Kupke, Sascha Young, Riedel, Dietmar, Frensing, Timo, Zmora, Pawel, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364022/
https://www.ncbi.nlm.nih.gov/pubmed/30463972
http://dx.doi.org/10.1128/JVI.01786-18