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A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome
Defective interfering particles (DIPs) replicate at the expense of coinfecting, fully infectious homologous virus. Typically, they contain a highly deleted form of the viral genome. Utilizing single-cell analysis, here we report the discovery of a yet-unknown DIP type, derived from influenza A virus...
Autores principales: | Kupke, Sascha Young, Riedel, Dietmar, Frensing, Timo, Zmora, Pawel, Reichl, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364022/ https://www.ncbi.nlm.nih.gov/pubmed/30463972 http://dx.doi.org/10.1128/JVI.01786-18 |
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