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Cell Cycle Arrest in G(2)/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression

Vesicular stomatitis virus (VSV) (a rhabdovirus) and its variant VSV-ΔM51 are widely used model systems to study mechanisms of virus-host interactions. Here, we investigated how the cell cycle affects replication of these viruses using an array of cell lines with different levels of impairment of an...

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Detalles Bibliográficos
Autores principales: Bressy, Christian, Droby, Gaith N., Maldonado, Bryant D., Steuerwald, Nury, Grdzelishvili, Valery Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364032/
https://www.ncbi.nlm.nih.gov/pubmed/30487274
http://dx.doi.org/10.1128/JVI.01885-18