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Neuroprotective effect of solanesol against 3-nitropropionic acid-induced Huntington's disease-like behavioral, biochemical, and cellular alterations: Restoration of coenzyme-Q10-mediated mitochondrial dysfunction

OBJECTIVE: The aim of the present study was to evaluate the solanesol (SNL)-mediated coenzyme-Q10 restoration to ameliorate 3-nitropropionic (3-NP)-induced behavioral, biochemical, and histological changes which resemble Huntington's disease (HD)-like symptoms in men. MATERIALS AND METHODS: Var...

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Detalles Bibliográficos
Autores principales: Mehan, Sidharth, Monga, Vikramdeep, Rani, Manju, Dudi, Rajesh, Ghimire, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364342/
https://www.ncbi.nlm.nih.gov/pubmed/30783323
http://dx.doi.org/10.4103/ijp.IJP_11_18