Recent advances in understanding RAG deficiencies

Recombination-activating genes ( RAG) 1 and RAG2 initiate the molecular processes that lead to lymphocyte receptor formation through VDJ recombination. Nonsense mutations in RAG1/ RAG2 cause the most profound immunodeficiency syndrome, severe combined immunodeficiency (SCID). Other severe and less-s...

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Detalles Bibliográficos
Autor principal: Gennery, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364374/
https://www.ncbi.nlm.nih.gov/pubmed/30800289
http://dx.doi.org/10.12688/f1000research.17056.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364374/
https://www.ncbi.nlm.nih.gov/pubmed/30800289
http://dx.doi.org/10.12688/f1000research.17056.1

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