Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan

BACKGROUND: Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB). The prodrug (PZA) is converted to its active form, pyrazinoic acid (POA) by MTB pncA-encoded pyrazinamidase (PZase...

Descripción completa

Detalles Bibliográficos
Autores principales: khan, Muhammad Tahir, Malik, Shaukat Iqbal, Ali, Sajid, Masood, Nayyer, Nadeem, Tariq, Khan, Anwar Sheed, Afzal, Muhammad Tanvir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364397/
https://www.ncbi.nlm.nih.gov/pubmed/30728001
http://dx.doi.org/10.1186/s12879-019-3764-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364397/
https://www.ncbi.nlm.nih.gov/pubmed/30728001
http://dx.doi.org/10.1186/s12879-019-3764-2

Ejemplares similares