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Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling

BACKGROUND: Animal production workers are persistently exposed to organic dust and can suffer from a variety of respiratory disease symptoms and annual decline in lung function. The role of high mobility group box-1 (HMGB1) in inflammatory airway diseases is emerging. Hence, we tested a hypothesis t...

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Detalles Bibliográficos
Autores principales: Bhat, Sanjana Mahadev, Massey, Nyzil, Karriker, Locke A., Singh, Baljit, Charavaryamath, Chandrashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364446/
https://www.ncbi.nlm.nih.gov/pubmed/30728013
http://dx.doi.org/10.1186/s12931-019-0992-3