Extensive sex differences at the initiation of genetic recombination

Meiotic recombination differs between males and females; however, when and how these differences are established is unknown. Here we identify extensive sex differences at recombination initiation by mapping hotspots of meiotic DNA double-strand breaks in male and female mice. Contrary to past findin...

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Detalles Bibliográficos
Autores principales: Brick, Kevin, Thibault-Sennett, Sarah, Smagulova, Fatima, Lam, Kwan-Wood G., Pu, Yongmei, Pratto, Florencia, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364566/
https://www.ncbi.nlm.nih.gov/pubmed/30185906
http://dx.doi.org/10.1038/s41586-018-0492-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364566/
https://www.ncbi.nlm.nih.gov/pubmed/30185906
http://dx.doi.org/10.1038/s41586-018-0492-5

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