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Extensive sex differences at the initiation of genetic recombination
Meiotic recombination differs between males and females; however, when and how these differences are established is unknown. Here we identify extensive sex differences at recombination initiation by mapping hotspots of meiotic DNA double-strand breaks in male and female mice. Contrary to past findin...
Autores principales: | Brick, Kevin, Thibault-Sennett, Sarah, Smagulova, Fatima, Lam, Kwan-Wood G., Pu, Yongmei, Pratto, Florencia, Camerini-Otero, R. Daniel, Petukhova, Galina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364566/ https://www.ncbi.nlm.nih.gov/pubmed/30185906 http://dx.doi.org/10.1038/s41586-018-0492-5 |
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