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Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction

Sirt1 is an NAD-dependent, class III deacetylase that functions as a cellular energy sensor. In addition to its well-characterized effects in peripheral tissues, emerging evidence suggests that neuronal Sirt1 activity plays a role in the central regulation of energy balance and glucose metabolism. I...

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Detalles Bibliográficos
Autores principales: Rickert, Emily, Fernandez, Marina O, Choi, Irene, Gorman, Michael, Olefsky, Jerrold M, Webster, Nicholas J G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364627/
https://www.ncbi.nlm.nih.gov/pubmed/30746504
http://dx.doi.org/10.1210/js.2018-00318