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Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction
Sirt1 is an NAD-dependent, class III deacetylase that functions as a cellular energy sensor. In addition to its well-characterized effects in peripheral tissues, emerging evidence suggests that neuronal Sirt1 activity plays a role in the central regulation of energy balance and glucose metabolism. I...
Autores principales: | Rickert, Emily, Fernandez, Marina O, Choi, Irene, Gorman, Michael, Olefsky, Jerrold M, Webster, Nicholas J G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364627/ https://www.ncbi.nlm.nih.gov/pubmed/30746504 http://dx.doi.org/10.1210/js.2018-00318 |
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