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Collagen reorganization in cartilage under strain probed by polarization sensitive second harmonic generation microscopy

Type II collagen fibril diameters in cartilage are beneath the diffraction limit of optical microscopy, which makes the assessment of collagen organization very challenging. In this work we use polarization sensitive second harmonic generation (P-SHG) imaging to map collagen organization in articula...

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Detalles Bibliográficos
Autores principales: Mansfield, Jessica C., Mandalia, Vipul, Toms, Andrew, Winlove, C. Peter, Brasselet, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364654/
https://www.ncbi.nlm.nih.gov/pubmed/30958161
http://dx.doi.org/10.1098/rsif.2018.0611