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Synchronization of pancreatic islets by periodic or non-periodic muscarinic agonist pulse trains

Pulsatile insulin secretion into the portal vein from the many pancreatic islets of Langerhans is critical for efficient glucose homeostasis. The islets are themselves endogenous oscillators, but since they are not physically coupled it is not obvious how their oscillations are synchronized across t...

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Detalles Bibliográficos
Autores principales: Adablah, Joel E., Vinson, Ryan, Roper, Michael G., Bertram, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364940/
https://www.ncbi.nlm.nih.gov/pubmed/30726280
http://dx.doi.org/10.1371/journal.pone.0211832