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Synchronization of pancreatic islets by periodic or non-periodic muscarinic agonist pulse trains
Pulsatile insulin secretion into the portal vein from the many pancreatic islets of Langerhans is critical for efficient glucose homeostasis. The islets are themselves endogenous oscillators, but since they are not physically coupled it is not obvious how their oscillations are synchronized across t...
Autores principales: | Adablah, Joel E., Vinson, Ryan, Roper, Michael G., Bertram, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364940/ https://www.ncbi.nlm.nih.gov/pubmed/30726280 http://dx.doi.org/10.1371/journal.pone.0211832 |
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