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LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency

The molecular basis for the formation of functional, higher-ordered macro-molecular domains is not completely known. The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) genome forms a super-molecular domain structure during latent infection that is strictly dependent on the DNA binding of the viral n...

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Detalles Bibliográficos
Autores principales: De Leo, Alessandra, Deng, Zhong, Vladimirova, Olga, Chen, Horng-Shen, Dheekollu, Jayaraju, Calderon, Abram, Myers, Kenneth A., Hayden, James, Keeney, Frederick, Kaufer, Benedikt B., Yuan, Yan, Robertson, Erle, Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364946/
https://www.ncbi.nlm.nih.gov/pubmed/30682185
http://dx.doi.org/10.1371/journal.ppat.1007489