YwqL (EndoV), ExoA and PolA act in a novel alternative excision pathway to repair deaminated DNA bases in Bacillus subtilis

DNA deamination generates base transitions and apurinic/apyrimidinic (AP)-sites which are potentially genotoxic and cytotoxic. In Bacillus subtilis uracil can be removed from DNA by the uracil DNA-glycosylase through the base excision repair pathway. Genetic evidence suggests that B. subtilis YwqL,...

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Detalles Bibliográficos
Autores principales: Patlán, Adriana G., Ayala-García, Víctor M., Valenzuela-García, Luz I., Meneses-Plascencia, Jimena, Vargas-Arias, Pedro L., Barraza-Salas, Marcelo, Setlow, Peter, Brieba, Luis G., Pedraza-Reyes, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364969/
https://www.ncbi.nlm.nih.gov/pubmed/30726292
http://dx.doi.org/10.1371/journal.pone.0211653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364969/
https://www.ncbi.nlm.nih.gov/pubmed/30726292
http://dx.doi.org/10.1371/journal.pone.0211653

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