TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia

OBJECTIVE—: TCF7L2 (transcription factor 7-like 2) is a Wnt-regulated transcription factor that maintains stemness and promotes proliferation in embryonic tissues and adult stem cells. Mice with a coronary artery disease–linked mutation in Wnt-coreceptor LRP6 (LDL receptor-related protein 6) exhibit...

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Detalles Bibliográficos
Autores principales: Srivastava, Roshni, Rolyan, Harshvardhan, Xie, Yi, Li, Na, Bhat, Neha, Hong, Lingjuan, Esteghamat, Fatemehsadat, Adeniran, Adebowale, Geirsson, Arnar, Zhang, Jiasheng, Ge, Guanghao, Nobrega, Marcelo, Martin, Kathleen A., Mani, Arya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365015/
https://www.ncbi.nlm.nih.gov/pubmed/30567484
http://dx.doi.org/10.1161/ATVBAHA.118.311830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365015/
https://www.ncbi.nlm.nih.gov/pubmed/30567484
http://dx.doi.org/10.1161/ATVBAHA.118.311830

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