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Sphere-forming assay vs. organoid culture: Determining long-term stemness and the chemoresistant capacity of primary colorectal cancer cells
Three-dimensional (3D) cultures are indispensable for capturing tumor heterogeneity in colorectal cancer (CRC) in vitro. Although 3D cultures (such as sphere-forming assay and organoid culture) can partially preserve the morphological and molecular characteristics of primary CRC, whether these 3D cu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365025/ https://www.ncbi.nlm.nih.gov/pubmed/30664193 http://dx.doi.org/10.3892/ijo.2019.4683 |