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Sphere-forming assay vs. organoid culture: Determining long-term stemness and the chemoresistant capacity of primary colorectal cancer cells

Three-dimensional (3D) cultures are indispensable for capturing tumor heterogeneity in colorectal cancer (CRC) in vitro. Although 3D cultures (such as sphere-forming assay and organoid culture) can partially preserve the morphological and molecular characteristics of primary CRC, whether these 3D cu...

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Detalles Bibliográficos
Autores principales:	Zhao, Hui, Yan, Chang, Hu, Yibing, Mu, Lei, Huang, Kaiyu, Li, Qiling, Li, Xiaolan, Tao, Deding, Qin, Jichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365025/ https://www.ncbi.nlm.nih.gov/pubmed/30664193 http://dx.doi.org/10.3892/ijo.2019.4683

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