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Bile acids promote gastric intestinal metaplasia by upregulating CDX2 and MUC2 expression via the FXR/NF-κB signalling pathway

Bile acids serve a critical role in the induction of gastric intestinal metaplasia (IM) and gastric carcinogenesis. The present study investigated the effects of bile acids on the induction of gastric IM formation. The results demonstrated that the expression levels of caudal-related homeobox transc...

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Detalles Bibliográficos
Autores principales: Yu, Jun-Hui, Zheng, Jian-Bao, Qi, Jie, Yang, Kui, Wu, Yun-Hua, Wang, Kai, Wang, Chun-Bao, Sun, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365039/
https://www.ncbi.nlm.nih.gov/pubmed/30747230
http://dx.doi.org/10.3892/ijo.2019.4692