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Identification of antiproliferative emodin analogues as inhibitors of epidermal growth factor receptor in cancer
A series of emodin analogues have been demonstrated to exhibit potent antiproliferative activity in three human epidermal growth factor receptor 2 (HER2)-overexpressing cell lines. However, in docking simulations, not all of these emodin analogues docked into the HER2 protein binding site. As the ep...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365047/ https://www.ncbi.nlm.nih.gov/pubmed/30664170 http://dx.doi.org/10.3892/ijmm.2019.4066 |