High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms

Negative-strand RNA viruses condense their genome into helical nucleocapsids that constitute essential templates for viral replication and transcription. The intrinsic flexibility of nucleocapsids usually prevents their full-length structural characterisation at high resolution. Here, we describe pu...

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Detalles Bibliográficos
Autores principales: Arragain, Benoît, Reguera, Juan, Desfosses, Ambroise, Gutsche, Irina, Schoehn, Guy, Malet, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365055/
https://www.ncbi.nlm.nih.gov/pubmed/30638449
http://dx.doi.org/10.7554/eLife.43075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365055/
https://www.ncbi.nlm.nih.gov/pubmed/30638449
http://dx.doi.org/10.7554/eLife.43075

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