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High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms

Negative-strand RNA viruses condense their genome into helical nucleocapsids that constitute essential templates for viral replication and transcription. The intrinsic flexibility of nucleocapsids usually prevents their full-length structural characterisation at high resolution. Here, we describe pu...

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Detalles Bibliográficos
Autores principales:	Arragain, Benoît, Reguera, Juan, Desfosses, Ambroise, Gutsche, Irina, Schoehn, Guy, Malet, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365055/ https://www.ncbi.nlm.nih.gov/pubmed/30638449 http://dx.doi.org/10.7554/eLife.43075

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