Cargando…

Rapamycin-induced miR-30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Vascular senescence is considered to be an independent risk factor for cardiovascular diseases. The present study aimed to investigate the effects of rapamycin on miR-30a and its relationship with autophagy and senescence in vascular smooth muscle cells (VSMCs). Young and aging VSMCs were treated wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Pan, Wang, Haiqin, Zhan, Junkun, Ma, Xinyu, Cui, Xingjun, Wang, Yanjiao, Wang, Yi, Zhong, Jiayu, Liu, Youshuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365076/
https://www.ncbi.nlm.nih.gov/pubmed/30747228
http://dx.doi.org/10.3892/ijmm.2019.4074